Peptide blends explained: Wolverine, GLOW and KLOW
Wolverine, GLOW and KLOW are market names, not chemical names. Nobody owns them and no standard fixes what goes inside, so the same name can describe different amounts from one supplier to the next. A blend is simply several separate peptides sharing one vial, which is why the label and the certificate matter more than the name.
What is in each blend
| Name | Peptides inside | Common total | Common split |
|---|---|---|---|
| Wolverine (BPC-157 + TB-500) | BPC-157, TB-500 | 10 or 20 mg | 5 + 5 mg, or 10 + 10 mg |
| GLOW | GHK-Cu, BPC-157, TB-500 | 70 mg | 50 + 10 + 10 mg |
| KLOW | GHK-Cu, KPV, BPC-157, TB-500 | 80 mg | 50 + 10 + 10 + 10 mg |
These are the most common versions on the market. GLOW also circulates at other totals, such as 50 and 90 mg, with different ratios. Always work from the amounts printed on your own vial.
What each component has been studied for
BPC-157. A synthetic 15-amino-acid peptide based on a sequence described in gastric juice. Most of the work is in rodents and cell culture, focused on tendon, muscle and ligament models and on blood vessel growth signals.
TB-500. A seven-amino-acid fragment (Ac-LKKTETQ) of thymosin beta-4, the part of that 43-amino-acid protein that binds actin. Much of the wound-healing literature used the full-length protein, not the fragment, so the two should not be read as interchangeable.
GHK-Cu. A three-amino-acid peptide bound to copper, studied mainly in skin and connective tissue models and in gene expression work. It is usually the largest share of GLOW and KLOW by weight.
KPV. A three-amino-acid fragment from the end of the hormone alpha-MSH, studied in cell and mouse models of intestinal inflammation.
What has been studied as a blend
Very little. Component research does not tell you how a mixture behaves, and the published record on the mixtures themselves is thin.
- BPC-157 with TB-500: we found one controlled study of the pair. In a 2026 experiment, 32 rats with repaired Achilles tendons were split into control, BPC-157, TB-500 and combined groups. Treated groups showed signs of better tendon structure than controls, most clearly with TB-500, but the combination added nothing measurable over either peptide alone. The authors called the study exploratory.
- GLOW and KLOW: we found no published controlled study of either blend (PubMed search, November 2026).
The math for a blend
Each peptide gets its own concentration, so work through them one at a time. Divide the amount of each peptide by the liquid added:
| Vial | Liquid added | Concentration of each peptide |
|---|---|---|
| BPC-157 10 mg + TB-500 10 mg | 2 mL | BPC-157 5 mg/mL, TB-500 5 mg/mL |
| GLOW 70 mg (50 + 10 + 10) | 5 mL | GHK-Cu 10 mg/mL, BPC-157 2 mg/mL, TB-500 2 mg/mL |
| KLOW 80 mg (50 + 10 + 10 + 10) | 5 mL | GHK-Cu 10 mg/mL, KPV 2 mg/mL, BPC-157 2 mg/mL, TB-500 2 mg/mL |
The total on the label (70 or 80 mg) is not useful for this on its own. Our reconstitution math guide covers the method, and the ratio stays fixed once mixed, so you cannot change one peptide's concentration without changing the others.
Reading a blend's certificate
A blend asks more of a certificate of analysis than a single peptide does:
- Every component should be named, with its amount, not just the total.
- Expect several main peaks on the HPLC trace, one for each peptide. A single overall purity figure says little about the balance between them.
- Mass spectrometry should identify each peptide, with an observed mass for every component.
Handling notes
- A blue tint is expected in blends containing GHK-Cu, because the copper complex is blue.
- Each peptide degrades in its own way. We are not aware of published stability data for these specific mixtures, so follow the general rules in storing peptides and date every vial.
Sources
- Biçer O, et al. Effects of BPC-157 and TB-500 on Achilles tendon healing in rats. Jt Dis Relat Surg, 2026. Source
- Gwyer D, et al. Gastric pentadecapeptide BPC 157 and its role in accelerating musculoskeletal soft tissue healing. Cell Tissue Res, 2019. Source
- Chang CH, et al. The promoting effect of pentadecapeptide BPC 157 on tendon healing. J Appl Physiol, 2011. Source
- Pickart L, Margolina A. Regenerative and protective actions of the GHK-Cu peptide. Int J Mol Sci, 2018. Source
- Dalmasso G, et al. PepT1-mediated tripeptide KPV uptake reduces intestinal inflammation. Gastroenterology, 2008. Source
- Kannengiesser K, et al. Melanocortin-derived tripeptide KPV has anti-inflammatory potential in murine models. Inflamm Bowel Dis, 2008. Source